|
|
|
|
A 29-year-old man developed acute cerebellar ataxia following Epstein-Barr virus infection.Serum IgG and IgM antibodies reacted with both nuclear and cytoplasmic elements of neurons.Western blot revealed IgG binding to the 34-and 29-kd bands and IgM binding to the 44-,37-,and 29-kd bands.The IgM reactivity gradually reduced.There was no identifiable neoplasm and the ataxia gradually improved.These findings suggest a role for autoimmune mechanisms in the pathogenesis of acute cerebellar ataxia. |
|